IHC identifies the presence and pattern of expression of proteins in a biological sample through specific antibody binding.
•The precise binding that occurs between an antibody and its target protein epitope enables the detection of highly specific amino acid sequences within a protein.
•Antibodies can also detect specific post-translational modifications (PTM) of a protein. Phospho-specific antibodies have been used to identify components of specific signaling pathways and to study changes in phosphorylation events in various biological contexts.
